It all depends on what kind of series you're into. If you like the more grimdark stuff then Higurashi no naku Koro ni or Another would be good choices. If you want an anime for the long haul (we're talking at least a year to watch all of the episodes, probably more) then Naruto or Bleach are excellent options. If cardgames are more your thing then I highly recommend Yu-Gi-Oh! If you want something a bit more grown up but avoiding the traps of pervertedness, then nothing is better than Spice and Wolf. If you want an emotional field trip, then Clannad, Angel Beats or AnoHana (no way I'm saying that thing's full name) are perfect. If you like a bit of nonsense nothingness then I highly recommend Asobi Ni Iku Yo (Cat Planet Cuties in english) and Lucky Star. If you're more into the fanservice and panty shots, then To Love-Ru and Highschool of the Dead are good (if you want to get SERIOUSLY ecchi mode, then Highschool DxD and Kiss x Sis are both good...but be warned, make sure no one else is around while you're watching those ones). Anyway, my list of great anime to watch are as follows: Sword Art Online (no arguments please, it's an opinion, I'm allowed to have one) Shingeki no Kyojin Yu-Gi-Oh! Mirai Nikki Higurashi No Naku Koro Ni Naruto Bleach Kiss x Sis Death Note Lucky Star Tokyo Mew Mew Highschool DxD That should give you a taste of every possible genre and hopefully give you a few series that you absolutely love. Enjoy!